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Pediatric Differences in Sex Development

When a child's gender is in question at birth, because genitals may not appear clearly male or female, the child is said to have ambiguous genitalia. Ambiguous genitalia can be a confusing and scary experience for parents, but these children are usually healthy. Ambiguous genitalia is more common than most people realize.


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Frequently Asked Questions

What are ambiguous genitalia?

What causes differences in sex development (DSD)?

Types of DSD

How is the gender determined in a child with ambiguous genitalia?

The physicians at the Positive Reevaluation of Urogenital Differences (PROUD) Clinic, formerly known as the Differences (Disorders) of Sexual Development Clinic, will work with your family to determine the best course of care for your child. In addition, the Children’s National PROUD team will provide expertise in many fields, as well as support through social work and psychology.

Providers Who Treat Differences in Sex Development

    Departments that Treat Differences in Sex Development

    Portrait of Young Girl Patient in Exam Room

    Psychiatry and Behavioral Sciences

    Psychiatry and Behavioral Sciences at Children's National offers assessment, diagnosis and care for children and teens with behavioral, emotional and developmental disorders.

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    Endocrinology and Diabetes

    Learn more about the Division of Endocrinology and Diabetes, which is a nationally recognized leader in treating a variety of endocrine disorders.

    Rare Disease Institute - Genetics and Metabolism

    Children's National Rare Disease Institute (CNRDI) is a first-of-its-kind center focused exclusively on advancing the care and treatment of children and adults with rare genetic diseases.