Condition
Pediatric Anemia (Megaloblastic or Pernicious)
What You Need to Know
In megaloblastic anemia, there is a decrease in red blood cells. The cells are too large and may be abnormally shaped.
Key Symptoms
The most common symptoms of megaloblastic anemia are similar to other types of anemia, such as:
- Tiredness
- Pale or yellow skin
- Fast heartbeat
- Shortness of breath
- Irritability or fussiness
Diagnosis
Doctors typically diagnose anemia by:
- Blood tests
- Hemoglobin and hematocrit
- Complete blood count (CBC)
- Peripheral smear
- Iron studies
Treatment
Megaloblastic anemia from vitamin deficiencies is treated by:
- Taking folate or B-12 supplements
- Eating more foods with these vitamins
Schedule an Appointment
Our pediatric specialists provide personalized care for your child’s physical, mental and emotional health needs. Meet the providers and schedule an appointment today.
Frequently Asked Questions
What is megaloblastic anemia in children?
What causes megaloblastic anemia in a child?
What are the symptoms of megaloblastic anemia in a child?
How is megaloblastic anemia diagnosed in a child?
How is megaloblastic anemia treated in a child?
What are possible complications of megaloblastic anemia in a child?
When should I call my child's healthcare provider?
Meet the Providers Who Treat Anemia (Megaloblastic or Pernicious)
Departments that Treat Anemia (Megaloblastic or Pernicious)

Blood Disorders (Hematology)
From sickle cell disease to histiocyte disorders, Children's National delivers expert care for any blood disorder diagnosis.