Pediatric Angelman Syndrome

Angelman syndrome can happen when a baby gets both copies of a part of chromosome #15 from the father. But Angelman syndrome most often happens when a chromosome #15 from each parent is present, but part of the mother’s chromosome is deleted. Then only the father's part is present. This causes Angelman syndrome symptoms to occur. 

People with Angelman syndrome can have these traits:

• Smaller head
• A wide jaw and spaced-out teeth
• Puffy-looking eyelids
• Short stature
• Severe intellectual disability with a lack of speech
• Stiff arm movements
• Spastic, uncoordinated walk
• Seizures
• Random outbursts of laughter