Pediatric Anemia (iron-deficiency)

Anemia is a common health problem in children. The most common cause of anemia is not getting enough iron. A child who's anemic doesn't have enough red blood cells or enough hemoglobin. Hemoglobin is a protein that lets red blood cells carry oxygen to other cells in the body. Iron is needed to form hemoglobin.

Iron-deficiency anemia can be caused by:

• Diets low in iron. A child gets iron from the food in their diet. But only a small amount of the iron in food is actually absorbed by the body.
  • Full-term newborns, born to a healthy birth parent, have iron that they get during the last 3 months of pregnancy.
  • Infants of a birth parent with anemia or other health problems may not have enough iron stored. And infants born early may not get enough iron.
  • At 4 to 6 months of age, the iron stored during pregnancy is at a low level. And more iron is used as the infant grows.
  • The American Academy of Pediatrics (AAP) advises feeding your baby only breastmilk for the first 6 months. Because breastmilk doesn't contain a lot of iron, infants who are breastfed only may not get enough iron in their diet.
  • Older infants and toddlers may not get enough iron from their diets.
• Body changes. When the body goes through a growth spurt, it needs more iron for making more red blood cells.
• Gastrointestinal (GI) tract problems. Poor absorption of iron is common after some forms of GI surgeries. When you eat foods containing iron, most of the iron is absorbed in the upper small intestine. Any abnormalities in the GI tract could alter iron absorption and cause iron-deficiency anemia.
• Blood loss. Loss of blood can cause a decrease of iron. Sources of blood loss may include GI bleeding, menstrual bleeding or injury.

Contact your child's health care provider if your infant isn't nursing well or if your toddler or child has any of the signs of iron-deficiency anemia.

In most cases, anemia is diagnosed with simple blood tests. Routine anemia screening is done because anemia is common in children and they often have no symptoms.

• The AAP recommends anemia screening with a hemoglobin blood test for all infants at 12 months. The screening should also include a risk assessment. This is a group of questions to find risk factors for iron-deficiency anemia. Risk factors include feeding problems, poor growth, and special health care needs.
• If the hemoglobin level is low, more blood tests are done.
• If your child has a risk factor at any age, blood tests are done. 
• Blood tests for anemia may also be done during routine physical exam or checkups in children of any age.

Most anemia in children is diagnosed with these blood tests:

• Hemoglobin and hematocrit. This is often the first screening test for anemia in children. It measures the amount of hemoglobin and red blood cells in the blood.
• Complete blood count. A complete blood count checks the red and white blood cells, blood clotting cells (platelets), and sometimes, young red blood cells (reticulocytes). It includes hemoglobin and hematocrit and more details about the red blood cells.
• Peripheral smear. A small sample of blood is examined under a microscope. Blood cells are checked to see if they look normal or not.
• Iron studies. Blood tests can be done to measure the amount of iron in your child's body.

The most common symptoms of iron-deficiency anemia are:

• Pale skin.
• Being grouchy (irritable) or fussy.
• Lack of energy or tiring easily (fatigue).
• Fast heartbeat.
• Sore or swollen tongue.
• Enlarged spleen.
• Wanting to eat odd substances, such as dirt or ice (also called pica).

Treatment will depend on your child’s symptoms, age, and general health. It will also depend on how bad the condition is.

To prevent iron-deficiency anemia, the AAP says: 

• Starting at age four months, infants who are only breastfed or partly breastfed should be given a daily iron supplement until they begin eating iron-rich foods.
• Infants who are formula-fed don't need iron supplements. The formula has iron added to it. Whole milk shouldn't be given to infants less than 12 months old.
• Infants and toddlers from one to three years old should have foods rich in iron. They include cereal that has iron added, red meats and vegetables with iron. Fruits with vitamin C are also important. Vitamin C helps the body absorb the iron.

Treatment of iron-deficiency anemia includes:

• Iron supplements. Iron drops or pills are taken over several months to increase iron levels in the blood. Iron supplements can irritate the stomach and discolor bowel movements. They should be taken on an empty stomach or with orange juice to increase absorption. They are much more effective than dietary changes alone. If the child can’t take drops or pills, IV (intravenous) iron may be needed.
• Iron-rich diet. Eating a diet with iron-rich foods can help treat iron-deficiency anemia. Good sources of iron include:
  
  • Iron-enriched cereals, breads, pasta and rice.
  • Meats, such as beef, pork, lamb, liver and other organ meats.
  • Poultry, such as chicken, duck, turkey, (especially dark meat), and liver.
  • Fish, such as shellfish, including clams, mussels, and oysters, sardines and anchovies.
  • Leafy greens of the cabbage family, such as broccoli, kale, turnip greens and collards.
  • Legumes, such as lima beans and green peas; dry beans and peas, such as pinto beans, black-eyed peas and canned baked beans.
  • Yeast-leavened whole-wheat bread and rolls.

Iron-deficiency anemia may cause delayed growth and development.