Condition
Li-Fraumeni syndrome
Li-Fraumeni syndrome (LFS) is a genetic condition that causes a high risk for certain kinds of cancer. LFS can cause different symptoms from child to child, and even among people in the same family who have it.
What are common symptoms of Li-Fraumeni syndrome?
Classic Li-Fraumeni syndrome (LFS) is linked to an increased risk of many different types of cancer. These cancers can develop during childhood or adulthood, and some people with LFS may develop more than one cancer during their lifetime.
However, not everyone with LFS will develop cancer. Some children inherit a form called attenuated LFS, which is caused by a gene mutation that has lower penetrance. This means the mutation is less likely to cause cancer or may lead to milder effects.
Schedule an Appointment
Every child with Li-Fraumeni syndrome is affected differently by the condition. We are prepared to meet you where you are, provide information and support, as well as the most advanced diagnosis and treatment for any symptoms affecting your child. Meet the doctors and surgeons who treat Li-Fraumeni syndrome and schedule an appointment today.
Frequently Asked Questions
What should my child avoid to help lower their cancer risk?
What tumors can occur with Li-Fraumeni syndrome?
What causes Li-Fraumeni syndrome?
Departments that Treat Li-Fraumeni syndrome
Cancer Genetics Program
Our cancer genetics experts help answer important questions about your child's inherited risk for cancer.
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