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Mary Teresa Donofrio, MD

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The Center for Heart, Lung and Kidney Disease


Advanced Echocardiography
Cardiac Imaging
Co-Director, Cardiac Neurodevelopmental Outcome Program
Director, Fetal Heart Program
Fetal and Transitional Medicine

Specialties: Cardiac First Trimester Imaging Program, Maternal Fetal Consultation, Cardiology Post-Natal Follow-Up Clinic, Complex Congenital Heart Disease, Congenital Heart Disease and Anomalies, Fetal Echocardiogram

Board CertificationsAmerican Board of Pediatrics/Pediatric Cardiology
National Provider Identifier1386704633

Service LocationsChildren's National Medical Center - Sheikh Zayed Campus for Advanced Children's Medicine
111 Michigan Avenue, NW
Washington, DC 20010
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Phone: 202-476-5000

Children's Outpatient Center of Montgomery County
*Note: GPS and online direction tools such as MapQuest or Yahoo Maps do not work for this location. Please use "Driving Directions" provided below:

Shady Grove Medical Park
9850 Key West Avenue
Rockville, MD 20850
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Phone: 301-765-5400 or 800-787-0243
Fax: 301-765-5497
*Ambulatory Surgery Center 301-765-5500

Children's Outpatient Center of Northern Virginia

3023 Hamaker Court
Suite 300, Third Floor
Fairfax, VA 22031
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Phone: 571-226-8380
Fax: 571-226-8362

ABC Pediatric, PC

231 Park Hill Drive
Fredricksburg, VA 22401
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Phone: Appointments: 571-226-8317
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Mary T. Donofrio is a full time attending in cardiology, director of the fetal heart program, and co-director of echocardiography. Under her leadership, the Children’s team treats the fetus as an individual patient and specialized care begins before birth.

With her vision, she expanded the fetal heart program to include the Washington, DC, region’s only First Trimester Fetal Cardiac Imaging Program, where we can detect heart abnormalities in high-risk pregnancies as early as 12 weeks gestation.

Dr. Donofrio specializes in fetal diagnosis and in-utero management of congenital heart disease, first trimester fetal cardiac imaging, fetal echocardiography, pediatric transthoracic and transesophageal echocardiography, delivery room management and transitional care for complex disease, and complex congenital heart disease management.

She also plays a leadership role in our echocardiography laboratory and serves as director of the Advanced Cardiac Imaging fellowship.

Dr. Donofrio joined the staff at Children’s National Medical Center after spending 9 years at the Virginia Commonwealth University School of Medicine, directing the echocardiography laboratory. She completed her cardiology fellowship training at Children’s Hospital of Philadelphia and performed advanced training in fetal echocardiography at Yale University. Dr. Donofrio is a fellow of the American College of Cardiology, American Academy of Pediatrics, and American Society of Echocardiography.

Her research has focused on autoregulation of cerebral blood flow in fetuses with congenital heart disease. She is a national expert in the areas of fetal cardiology, echocardiology, and pediatric cardiology. Dr. Donofrio was on several journal editorial boards, research committees, and has published over 50 papers and abstracts.

Dr. Donofrio is married and has two children. She grew up in Delaware and currently resides in Maryland. Her interests include the theater and music.

TypeSchoolLocationDegreeField of StudyYears
Undergraduate Education Johns Hopkins University Baltimore, MDBachelor of Arts 1982 -1985
Medical School Mount Sinai School of Medicine New York, NYDoctor of Medicine 1985 -1989
National & International Recognitions
Top DoctorsNorthern Virginia Magazine2013
Super DoctorsWashington Post Magazine2011
Top Doctors in Northern Virginia2009
Best Doctors in America2009
Top Doctors in Washington2008
Best Doctors in America2007
Richmond’s Top Doctors for KidsPediatric Cardiology2002

Affiliations and Memberships
TitleInstitutionCommittee / SectionYears
MemberSociety of Pediatric Echocardiology1995 - 2009
MemberAmerican Society of Echocardiology1995 - 2009
MemberRichmond Pediatric Society1995 - 2004
MemberRichmond Academy of Medicine1995 - 2004
Board MemberAmerican Heart AssociationRichmond Chapter2000 - 2004
TitleStudy NameInstitutionYears
Principal InvestigatorMonitoring of Cerebral Hypoxia with NIRS: Correlation with Neurologic Structural and Functional Outcome in Patients at Risk with Congenital Heart Disease
Principal InvestigatorAnalysis of Normal Cerebral Oxygenation and Correlation with Neurodevelopmental Exam in Full Term Infants
InvestigatorPostoperative complications after the Fontan procedure: Role of aprotinin
Principal InvestigatorNormative Echocardiographic Z-Score Measurements of Blood Vessels, Valve Dimensions, Chamber Dimensions and Cardiac Functional and Hemodynamic Measurements in Fetuses
Principal InvestigatorCorrelation of Prenatal Cerebral Blood Flow with Postnatal Preoperative Cerebral Oxygenation
Book Chapter, Donofrio M.T., Jonas R.A (2009), Impact of Congenital Heart Disease and Surgical Intervention on Neurodevelopment, In Charles Kleinman and Istvan Seri, Hemodynamics and Cardiology: Neonatal Questions and Controversies.

Journal Article, Krishnan A., Donofrio M.T. (2008), Spectrum of Fetal Echocardiographic Findings in Fetuses of Women with Clinical or Serological Evidence of Systemic Lupus Erythematosus, Journal of Maternal Fetal Medicine, 21, 776-782.

Conference Presentation - Poster, Donofrio M.T., Krishnan A., Gellis L., Chang T., Brown J., Zurakowsky D., Jonas R.A (2008), Aorta Size Predicts Cerebral Oxygenation in HLHS Neonates: Pediatric Academic Society, Poster session presented at the Pediatric Academic Society

Journal Article, Pike J, Krishnan A, Kaltman J, Donofrio MT (2008), Fetal and Neonatal Arrhythmias: Association with Maternal Diabetes and Neonatal Macrosomia, Journal of Perinatology.

Journal Article, Sanders SP, Colan SD, Cordes TM, Donofrio MT, Ensing GJ, Geva T, Kimball T, Sahn DJ, Silverman NH, Sklansky MS, Weinberg PM (2005), ACCF/AHA/AAP Recommendations for Training in Pediatric Cardiology. Task Force 2: Pediatric Training Guidelines for Noninvasive Cardiac Imaging, Journal of the American College of Cardiology, 46, 1384.

Journal Article, Donofrio M. T (2005), Innovations in Fetal Cardiology: Medical and Catheter Intervention Therapy, Heart Views, 6, 5-17.

Other, Donofrio M.T., Gullquist S.D, Mehta, I., Moskowitz, W.B (2004), Journal of Perinatology, Complete Heart Block: Fetal Management Protocol, Review of the Literature, and Report of the Smallest Successful Pacemaker Implantation, 24, 112-117.

Journal Article, Donofrio M.T., Bremer Y.A., Moskowitz W.B (2004), Diagnosis and Management of Restricted or Closed Foramen Ovale in Fetuses with Congenital Heart Disease, American Journal of Cardiology, 94, 1348-1351.

Journal Article, Donofrio M.T., Bremer Y.A., Gennings C., Schieken R.M., Gennings C., Morton L.D., Eidem B.W., Cetta F., Falkensammer C.B., Huhta J.C., Kleinman C.S (2003), Autoregulation of Cerebral Blood Flow in Fetuses with Congenital Heart Disease: The Brain Sparing Effect. A Multicenter Study, Pediatric Cardiology, 24, 436-444.

Journal Article, Donofrio, M.T. , The Heart-Brain Interaction in the Fetus: Cerebrovascular Blood Flow in the Developing Human, Progress in Pediatric Cardiology, 22, 2006, 41-52.

For a more comprehensive list of publications for Mary Donofrio, MD view the National Library of Medicine’s PubMed online database

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