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Brian Richard Rood, MD

The Center for Cancer and Blood Disorders

Departments
Oncology

Programs
Brain Tumor Institute (Neuro-Oncology Program)
Neurofibromatosis Institute
Pediatric Advanced Needs Assessment and Care Team (PANDA)


Children’s Research Institute (CRI)
Center for Cancer and Immunology Research
View CRI Profile for Brian Richard Rood
Specialties: Brain Tumors

Board CertificationsAmerican Board of Pediatrics
American Board of Pediatrics/Hematology-Oncology
National Provider Identifier1881773943
E-Mail

Service LocationsChildren's National Medical Center - Sheikh Zayed Campus for Advanced Children's Medicine
111 Michigan Avenue, NW
Washington, DC 20010
Map | Driving Directions

Phone: 202-476-5000
Biography

Brian Richard Rood, MD, is the medical director of the Pediatric Advanced Needs Assessment (PANDA Care Team) and a member of the Neuro-Oncology Program at Children's National Medical Center. Dr. Rood also is a board member of the DC Pediatric Palliative Care Collaboration.

Dr. Rood's primary clinical and research interest is brain tumors. He is the chair of a multi-institutional study of cerebrospinal fluid proteomics for the Pediatric Brain Tumor Consortium.

Dr. Rood has two children. His favorite past times include designing and building furniture, sailing, reading, and playing the mandolin.
Education
TypeSchoolLocationDegreeField of StudyYears
Undergraduate Education Pennsylvania State University University Park, PABachelor of Arts English Literature 1987 -1991
Medical School Jefferson Medical College Philadelphia, PADoctor of Medicine Medicine 1991 -1995
National & International Recognitions
AwardInstitutionEventYear
Super DoctorsWashington Post Magazine2011
Top DoctorsU.S. News and World Report2011
New Palliative Care AwardCare First Blue Cross Blue Shield2009
Phi Mu Dinah Armstrong Kukes Award2004
Fellowship in Genetics and NeuroscienceWilliam A. Haseltine Foundation for Medical Science and the Arts2002
Pine Tree Apple Research FellowNational Childhood Cancer Foundation1999

Affiliations and Memberships
TitleInstitutionCommittee / SectionYears
SecretaryDC Pediatric Palliative Care CollaborationBoard of Directors2006 - 2009
Active MemberPediatric Brain Tumor Consortium2001 - 2009
Active MemberChildren’s Oncology Group2001 - 2009
Medical DirectorCamp Friendship2008 - 2009
MemberChildhood Brain Tumor FoundationMedical Scientific Advisory Board2007 - 2009
MemberInspireScientific and Medical Advisory Committee2008 - 2009
Research
TitleStudy NameInstitutionYears
Principal InvestigatorCreation of a platelet-derived growth factor -C Autocrine Loop by hypermethylation in Cancer 1 InactivationNational Institutes of Health2007 - 2012
Principal InvestigatorHope Street KidsHope Street Kids Research 2007 - 2009
Principal InvestigatorN-08: Evaluation of cerebral spinal fluid (CSF) proteome in children with newly diagnosed central nervous system tumorsPediatric Brain Tumor Consortium
InvestigatorA phase I/II trial of external beam radiation therapy and cetuximab followed by irinotecan and cetuximab for children and young adults with newly diagnosed diffuse pontine tumors and high-grade astrocytomasPediatric Oncology Experimental Therapeutics Investigator Consortium
Read more about the research interests of Brian Richard Rood
Publications
Journal Article, Rood, B.R., Van Rechem, C., Touka, M., Pinte, S., Jenal, M., Guerardel, C., Ramsey, K., Monte, D., Begue, A., Tschan, M., Stephan, D., Leprice, D. (2009), The scavenger chemokine (C-X-C motif) receptor 7 (CXCR7) is a direct target gene of hypermethylated in cancer 1 (HIC1), Journal of Biological Chemistry.

Journal Article, Fleuriel, C., Touka, M., Boulay, G., Guerardel, C., Rood, B.R., Leprince, C. (2009), HIC1 (Hypermethylated in Cancer 1) epigenetic silencing in tumors, The International Journal of Biochemistry & Cell Biology, 41, 1, 26-33.

Journal Article, Pistollato, F., Chen, H.L., Rood, B.R., Zhang, H., D'Avella, D., Denaro, L., Gardiman, M., te Kronnie, G., Schwartz, P.H., Favaro, E., Indraccolo, S., Basso, G., Panchision, D. (2008), Hypoxia and HIF1a Repress the Differentiative Effects of BMPs in High Grade Glioma, Stem Cells.

Journal Article, Choi, M.R., Rood, B.R., Kamani, N., Lafond, D.L., Packer, R.J., Santi, M.R., MacDonald, T.J. (2008), Feasibility of Metronomic Chemotherapy Following High Dose Chemotherapy for Malignant Central Nervous System Tumors, Pediatric Blood Cancer, 50, 970-975.

Journal Article, Thorarinsdottir, H.K., Rood, B., Kamani, N., Lafond, D., Perez-Albuerne, E., Loechelt, B., Packer, R.J., Macdonald, T.J. (2006), Outcome for children <4 years of age with malignant central nervous system tumors treated with high-dose chemotherapy and autologous stem cell rescue, Pediatric Blood Cancer.

Journal Article, Rood, B.R., MacDonald, T.J. (2005), Pediatric High Grade Glioma: Molecular Genetic Clues for Innovative Therapeutic Approaches, Journal of Neuro-Oncology, 75, 3, 267-272.

Journal Article, Rood, B.R., MacDonald, T.J., Packer, R.J. (2004), Current treatment of medulloblastoma: Recent advances and future challenges, Seminars in Oncology, 31, 5, 666-675.

Journal Article, Pinte S, Stankovic-Valentin N, Deltour S, Rood BR, Guerardel C, Leprince D (2004), The Tumor Suppressor Gene HIC1 (Hypermethylated in Cancer 1) is a Sequence-Specific Transcriptional Repressor., Journal of Biologic Chemistry , 279, 38313-38324.

Journal Article, Rood, BR., Zhang, H.Z., Cogen, P.H. (2004), Inter-cellular Heterogeneity of Expression of the MGMT DNA Repair Gene in Pediatric Medulloblastoma., Neuro-Oncology, 6, 3, 200-207.

Journal Article, Rood, B.R., Zhang, H.Z., Weitman, D.M., Cogen, P.H. (2002), Hypermethylation of HIC-1 and 17p Allelic Loss in Medulloblastoma, Cancer Research, 62, 3794-3797.


For a more comprehensive list of publications for Brian Rood, MD view the National Library of Medicine’s PubMed online database
 


   
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