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Ljubica Caldovic, PhD
Children's National Medical Center

Principal Investigator, Children's Research Institute (CRI), Center for Genetic Medicine Research (CGMR)

George Washington University
School of Medicine and Health Sciences
Assistant Professor, Pediatrics

Contact Information
Children's National Medical Center
Center for Genetic Medicine Research (CGMR)
111 Michigan Avenue, NW
Washington, DC 20010-2970

202-476-6029
Icaldovic@cnmcresearch.org

Education & Training
Institution & Location Degree Year(s) Field of Study
University of Belgrade, Belgrade, Yugoslavia BS 1988 Chemistry
University of Minnesota, Minneapolis, MN PhD 1998 Molecular, Cellular and Developmental Biology and Genetics

Research Interests
Ljubica Caldovic, MD, is an assistant professor in the Research Center for Genetic Medicine at Children’s National Medical Center. She earned her PhD from the University of Minnesota in 1998. She is interested in mechanisms that the body uses to sense its environment and regulate its metabolism. She has been studying regulation of the urea cycle, a metabolic pathway responsible for disposal of neurotoxic ammonia from the body and trying to understand how the body senses changes in the ammonia load and adjusts levels of urea cycle enzymes and urea production. She has been using several approaches to address this problem: examination of proteins that interact with the urea cycle enzymes and have potential to regulate their levels or activity, transcriptional and proteomic profiling to examine global changes that accompany changes in ammonia load, and study of the function of the cycle throughout evolution.


Publications
View a partial list of publications for (Ljubica Caldovic) through the National Library of Medicine's PubMed online database.


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