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Mouse Drug Screening and Transgenics
Murine preclinical drug testing and phenotyping facility
The Mouse Drug Screening and Phenotyping Core maintains and provides several dystrophy mouse strains to investigators, performs comprehensive phenotyping, and conduct preclinical trials for neuromuscular disease models. Having access to the mouse models allows scientists to test treatments and to learn more about how these diseases develop and progress with time.
Services include
- Behavioral assays
- Body weight
- Grip Strength Meter
- Rotarod
- Voluntary Wheel
- Treadmill
- Digiscan
- Imaging
- Echocardiography
- Magnetic Resonance Imaging (via Howard University)
- Optical Imaging
- Functional assays
- In-vitro muscle force measurements
- Histological evaluation
- Hematoxylin-Eosin
- Sirius red
- Evans Blue Dye
- Ceatine Kinase
- Molecular assays
- Western Blotting
- Gene expression profiling
Faculty of this core facility include
Related links
- This core facility is a project of the Wellstone-DC program at Children’s National Medical Center.
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