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David Alex Jacobsohn, MD, ScM

The Center for Cancer and Blood Disorders

Division Chief, Blood and Marrow Transplantation

Board CertificationsAmerican Board of Pediatrics
American Board of Pediatrics/Hematology-Oncology
National Provider Identifier1346200250

Service LocationsChildren's National Medical Center - Sheikh Zayed Campus for Advanced Children's Medicine
111 Michigan Avenue, NW
Washington, DC 20010
Map | Driving Directions

Phone: 202-476-5000

David Jacobsohn, MD, Chief of Bone Marrow Transplant, joins Children's National from Children’s Memorial Hospital in Chicago, where he served as a member of the Stem Cell Transplant Program staff and as the Director of the Chronic Graft-versus-Host Disease Clinic. He has lectured widely on GvHD/BMT in Europe, Latin America, and the United States. Dr. Jacobsohn obtained a Bachelor of Science from Yale University, his medical degree from Tufts University, and a Masters in Clinical Investigation from from Johns Hopkins School of Hygiene and Public Health.
TypeSchoolLocationDegreeField of StudyYears
Undergraduate Education Yale University New Haven, CTBachelor of Science 1988 -1992
Medical School Tufts University School of Medicine Boston, MADoctor of Medicine 1992 -1996
Post Graduate Education Johns Hopkins School of Public Health Baltimore, MD 2001
National & International Recognitions
Outstanding Faculty Performance in a Problem Based Learning 2007-2008Northwestern University Feinberg School of Medicine2008
Visiting ProfessorshipColumbia University Hematology/Oncology/Transplant2006

Affiliations and Memberships
TitleInstitutionCommittee / SectionYears
MemberAmerican Society of Clinical Oncology2003
MemberAmerican Society of Hematology2003
MemberAmerican Society for Blood and Marrow Transplantation2003
MemberChildren's Oncology GroupHematopoietic Stem Cell Transplant Steering Committee2004
MemberPediatric Blood and Marrow Transplant Consortium2004
TitleStudy NameInstitutionYears
InvestigatorImmune Mediated Disorders after Allogenic HCTNational Institutes of Health Office of Rare Diseases2009 - 2014
InvestigatorImproving Outcomes Assessment in Chronic GVHDNational Institutes of Health2007 - 2012
Principal InvestigatorReduced Intensity Stem Cell Transplant in Children and Young Adults Utilizing Photopheresis, Fludarabine and Busulfan2005 - 2008
Principal InvestigatorA Phase II Study of Pentostatin for the Treatment of High-Risk of Refractory Chronic GVHD in Children2003 - 2007
Principal InvestigatorPediatric chronic GVHD Pharmacokinetics and bioavailability of IV methylprednisolone vs. oral prednisolone and studies of mechanisms that may affect oral bioavailabilityNational Center for Research Resources, National Institutes of Health2005 - 2006
Principal InvestigatorHemofiltration for Respiratory Failure Following Hematopoetic Stem Cell TransplantationStanford University2005 - 2006
Principal InvestigatorFeasibility of New Assessment Tools in the Evaluation of Chronic GVHD in Children2005 - 2006
Principal InvestigatorPentostatin in Refractory Chronic Graft Versus Host Disease2003 - 2004
Principal InvestigatorPhase I Study of MEDI-507 in the Treatment of Pediatric Patients with at Least Grade II Acute Graft-versus-Host Disease2003 - 2004
Journal Article, McNeer JL, Kletzel M, Rademaker A, Alford K, O'Day K, Schaefer C, Duerst R, Jacobsohn DA (2010), Early elevation of C-reactive protein correlates with severe infection and nonrelapse mortality in children undergoing allogeneic stem cell transplantation, Biol Blood Marrow Transplant, 16, 3, 350-357.

Journal Article, Jacobsohn DA (2010), Optimal management of chronic graft-versus-host disease in children, Br J Haematol, 150, 3, 278-292.

Journal Article, Jacobsohn, DA, Rademaker A, Kaup, M, Vogelsang, GB (2009), Skin response using NIH consensus criteria versus Hopkins scale in a Phase II study for steroid-refractory chronic GVHD, Bone Marrow Transplantation.

Journal Article, Jacobsohn DA, Tse WT, Chaleff S, Rademaker A, Duerst R, Olszewski M, Huang W, Chou PM, Kletzel M (2009), High WT1 gene expression before haematopoietic stem cell transplant in children with acute myeloid leukaemia predicts poor event-free survival , Br J Haematol, 146, 6, 669-674.

Journal Article, Jacobsohn DA, Gilman, AL, Rademaker A, Browning B, Grimley M, Lehmann L, Nemecek ER, Thormann K, Schultz KR, Vogelsang GB (2009), Evaluation of pentostatin in corticosteroid-refractory chronic graft versus-host disease in children: a Pediatric Blood and Marrow Transplant Consortium study, Blood, 114, 20, 4354-4360.

Journal Article, Jacobsohn, DA (2008), Acute graft-versus-host-disease in children, Bone Marrow Transplantation, 41, 2, 215-221.

Journal Article, Jacobsohn DA, Chen AR, Zahurak M, Piantadosi S, Anders V, Bolaños-Meade J, Higman M, Margolis J, Kaup M, Vogelsang, GB (2007), Phase II study of pentostatin in patients with corticosteroid-refractory chronic graft-versus-host disease, J Clin Oncol, 25, 27, 4255-4261.

Journal Article, Browning, B, Thormann, K, Seshadri, R, Duerst, R, Kletzel, M, Jacobsohn, DA (2006), Weight loss and reduced body mass index: a critical issue in children with multi-organ chronic graft-versus-host disease, Bone Marrow Transplantation, 37, 5, 527-533.

Journal Article, Jacobsohn, DA, Hewlett, B, Morgan, E, Tse, W, Duerst, R, Kletzel, M (2005), Favorable outcome for infant acute lymphoblastic leukemia following hematopoietic stem cell transplantation, Biology of Blood and Marrow Transplantation , 11, 999-1005.

Journal Article, Jacobsohn, DA., Duerst, R., Tse, W., Kletzel, M (2004), Reduced intensity haemopoietic stem cell transplantation for treatment of non-malignant diseases in children, Lancet, 364, 156-162.

For a more comprehensive list of publications for David Jacobsohn, MD, ScM view the National Library of Medicine’s PubMed online database

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