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Brian Richard Rood, MD
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Center of Excellence, Departments, and Programs
The Center for Cancer and Blood Disorders Oncology Brain Tumor Institute (Neuro-Oncology Program) Medical Director, Pediatric Advanced Needs Assessment and Care Team (PANDA)
Children’s Research Institute (CRI) Center for Cancer and Immunology Research View CRI Profile for Brian Richard Rood Specialties: Brain Tumors
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| Board Certifications |
General Pediatrics American Board of Pediatrics/Hematology-Oncology
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National Provider Identifier
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1881773943 |
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| Practice Locations |
Children's National Medical Center - Main Hospital 111 Michigan Avenue, NW Washington, DC Phone: 202-476-5000

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| Biography |
Brian Richard Rood, MD, is the medical director of the Pediatric Advanced Needs Assessment (PANDA Care Team) and a member of the Neuro-Oncology Program at Children's National Medical Center. Dr. Rood also is a board member of the DC Pediatric Palliative Care Collaboration.
Dr. Rood's primary clinical and research interest is brain tumors. He is the chair of a multi-institutional study of cerebrospinal fluid proteomics for the Pediatric Brain Tumor Consortium.
Dr. Rood has two children. His favorite past times include designing and building furniture, sailing, reading, and playing the mandolin.
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| Education |
| Type | School | Location | Degree | Field of Study | Years | | Undergraduate Education | Pennsylvania State University | University Park, PA | Bachelor of Arts | English Literature | 1987 -1991 | | Medical School | Jefferson Medical College | Philadelphia, PA | Doctor of Medicine | Medicine | 1991 -1995 |
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| Training |
| Type | Institution | Location | Position | Specialty | Years | | Fellowship Program | Children's National Medical Center | Washington, DC | | Research Fellowship | 2002 | | Residency Program | University of Vermont | Burlington, VT | Resident | Pediatrics | 1995 - 1998 | | Fellowship Program | Children's National Medical Center | Washington, DC | Fellow | | 1998 - 2001 |
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| National and International Recognition |
| Award | Institution | Event | Year | | New Palliative Care Award | Care First Blue Cross Blue Shield | | 2009 | | Phi Mu Dinah Armstrong Kukes Award | | | 2004 | | Fellowship in Genetics and Neuroscience | William A. Haseltine Foundation for Medical Science and the Arts | | 2002 | | Pine Tree Apple Research Fellow | National Childhood Cancer Foundation | | 1999 |
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| Affiliations and Memberships |
| Title | Institution | Committee / Section | Years | | Secretary | DC Pediatric Palliative Care Collaboration | Board of Directors | 2006 - 2009 | | Active Member | Pediatric Brain Tumor Consortium | | 2001 - 2009 | | Active Member | Children’s Oncology Group | | 2001 - 2009 | | Medical Director | Camp Friendship | | 2008 - 2009 | | Member | Childhood Brain Tumor Foundation | Medical Scientific Advisory Board | 2007 - 2009 | | Member | Inspire | Scientific and Medical Advisory Committee | 2008 - 2009 |
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| Research |
| Title | Study Name | Institution | Years | | Principal Investigator | Creation of a platelet-derived growth factor -C Autocrine Loop by hypermethylation in Cancer 1 Inactivation | National Institutes of Health | 2007 - 2012 | | | Principal Investigator | Hope Street Kids | Hope Street Kids Research | 2007 - 2009 | | | Principal Investigator | N-08: Evaluation of cerebral spinal fluid (CSF) proteome in children with newly diagnosed central nervous system tumors | Pediatric Brain Tumor Consortium | | | | Investigator | A phase I/II trial of external beam radiation therapy and cetuximab followed by irinotecan and cetuximab for children and young adults with newly diagnosed diffuse pontine tumors and high-grade astrocytomas | Pediatric Oncology Experimental Therapeutics Investigator Consortium | | | | Read more about the research interests of Brian Richard Rood |
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| Publications |
Journal Article, Rood, B.R., Van Rechem, C., Touka, M., Pinte, S., Jenal, M., Guerardel, C., Ramsey, K., Monte, D., Begue, A., Tschan, M., Stephan, D., Leprice, D. (2009), The scavenger chemokine (C-X-C motif) receptor 7 (CXCR7) is a direct target gene of hypermethylated in cancer 1 (HIC1), Journal of Biological Chemistry.
Journal Article, Fleuriel, C., Touka, M., Boulay, G., Guerardel, C., Rood, B.R., Leprince, C. (2009), HIC1 (Hypermethylated in Cancer 1) epigenetic silencing in tumors, The International Journal of Biochemistry & Cell Biology, 41, 1 , 26-33.
Journal Article, Pistollato, F., Chen, H.L., Rood, B.R., Zhang, H., D'Avella, D., Denaro, L., Gardiman, M., te Kronnie, G., Schwartz, P.H., Favaro, E., Indraccolo, S., Basso, G., Panchision, D. (2008), Hypoxia and HIF1a Repress the Differentiative Effects of BMPs in High Grade Glioma, Stem Cells.
Journal Article, Choi, M.R., Rood, B.R., Kamani, N., Lafond, D.L., Packer, R.J., Santi, M.R., MacDonald, T.J. (2008), Feasibility of Metronomic Chemotherapy Following High Dose Chemotherapy for Malignant Central Nervous System Tumors, Pediatric Blood Cancer, 50, 970-975.
Journal Article, Thorarinsdottir, H.K., Rood, B., Kamani, N., Lafond, D., Perez-Albuerne, E., Loechelt, B., Packer, R.J., Macdonald, T.J. (2006), Outcome for children <4 years of age with malignant central nervous system tumors treated with high-dose chemotherapy and autologous stem cell rescue, Pediatric Blood Cancer.
Journal Article, Rood, B.R., MacDonald, T.J. (2005), Pediatric High Grade Glioma: Molecular Genetic Clues for Innovative Therapeutic Approaches, Journal of Neuro-Oncology, 75, 3 , 267-272.
Journal Article, Rood, B.R., MacDonald, T.J., Packer, R.J. (2004), Current treatment of medulloblastoma: Recent advances and future challenges, Seminars in Oncology, 31, 5 , 666-675.
Journal Article, Pinte S, Stankovic-Valentin N, Deltour S, Rood BR, Guerardel C, Leprince D (2004), The Tumor Suppressor Gene HIC1 (Hypermethylated in Cancer 1) is a Sequence-Specific Transcriptional Repressor., Journal of Biologic Chemistry , 279 , 38313-38324.
Journal Article, Rood, BR., Zhang, H.Z., Cogen, P.H. (2004), Inter-cellular Heterogeneity of Expression of the MGMT DNA Repair Gene in Pediatric Medulloblastoma., Neuro-Oncology, 6, 3 , 200-207.
Journal Article, Rood, B.R., Zhang, H.Z., Weitman, D.M., Cogen, P.H. (2002), Hypermethylation of HIC-1 and 17p Allelic Loss in Medulloblastoma, Cancer Research, 62, 3794-3797.
For a more comprehensive list of publications for Brian Rood, MD view the National Library of Medicine’s PubMed online database |
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