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Phillip L. Pearl, MD


Center of Excellence, Departments, and Programs
The Center for Neuroscience and Behavioral Medicine
Division Chief, Neurology

Children’s Research Institute (CRI)
Center for Neuroscience Research
View CRI Profile for Phillip L. Pearl
Specialties: Epilepsy, Neurometabolic Disorders , Neurogenetic Disorders , Seizures

Board Certifications American Board of Psychiatry/Neurology-Neurophysio
American Board of Pediatrics
American Board of Psychiatry and Neurology
National Provider Identifier 1902983257

Practice Locations
Children's National Medical Center - Main Hospital
111 Michigan Avenue, NW
Washington, DC
Phone: 202-476-5000
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Children's Outpatient Center of Northern Virginia
8501 Arlington Boulevard
Suite 200
Fairfax, VA 22031
Phone: 571-226-8380
Fax: 571-226-8312
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Biography
Phillip L. Pearl, MD, is chief of the Division of Neurology, interim director of Developmental Pediatrics, and director of Medical Student Education (Neurology) at George Washington University School of Medicine. The division of General Neurology is one of the largest pediatric neurology practices in the area, serving the greater Washington, DC/Maryland/Northern Virginia region through outpatient centers located at Children's main campus, as well as through its Regional Outpatient Centers and a number of satellite offices. Dr. Pearl's research interests are focused in epilepsy and neurotransmitter disorders, specifically SSADH deficiency. He serves as an investigator in protocols at Children's National Medical Center and the National Institutes of Health, and in that capacity makes the best practices in pediatric neurological care available to the patients and families for whom he cares. In addition to his impressive work in clinical care and research, Dr. Pearl is a jazz musician and frequently plays at area venues, including Blues Alley.

Education
TypeSchoolLocationDegreeField of StudyYears
Undergraduate Education Johns Hopkins University Baltimore, MDBachelor of Arts 1980
Medical School University of Maryland School of Medicine Baltimore, MDDoctor of Medicine 1984

Training
TypeInstitutionLocationPositionSpecialtyYears
Residency Program Baylor College of Medicine Houston, TXResident Pediatrics 1984 - 1986
Fellowship Program Baylor College of Medicine Houston, TXFellow Neurology 1986 - 1989
Fellowship Program Harvard Medical School Boston, MAFellow Neurophysiology 1989 - 1990

National and International Recognition
AwardInstitutionEventYear
Best Doctors Northern Virginia Magazine2008
Distinguished Clinical TeacherGeorge Washington University School of Medicine2005
America’s Top PhysiciansConsumers’ Research Council of America2004
Humanism in Medicine2004
Faculty Award - Humanism in MedicineAssociation of American Medical Colleges

Affiliations and Memberships
TitleInstitutionCommittee / SectionYears
MemberAmerican Neurological Association2006 - 2009
MemberAmerican Pediatric Society2006 - 2009
ChairmanChild Neurology SocietyAwards Committee 2004 - 2009
Secretary/TreasurerProfessors of Child Neurology2006 - 2009
MemberAmerican Epilepsy SocietyPractice Committee2000 - 2003

Research
TitleStudy NameInstitutionYears
Principal InvestigatorClinical Studies on SSADH DeficiencyPediatric Neurotransmitter Disease Association2007 - 2009
Principal InvestigatorCerebral MRI Abnormalities Associated with Vigabatrin TherapyChildren's National Medical Center/ Institutional Review Board2006
InvestigatorCortical Excitability in SSADH Deficiency PatientsInstitutional Review Board/ National Institute of Neurological Disorders and Stroke/ National Instit2005
Principal InvestigatorCollection of Specimens for the Development of Diagnostic Assays of Neurotransmitter DisordersInstitutional Review Board2004
Principal InvestigatorQuestionnaire Study of SSADH DeficiencyInstitutional Review Board2004
Read more about the research interests of Phillip L. Pearl

Publications
Journal Article, Hsieh D. T., Pearl P. L (2009), Teaching Video NeuroImages: preserved awareness in a frontal seizure with bilateral motor involvement: a psychogenic mimic., Neurology, 72, 56-56.

Book Chapter, Pearl, P.L., Gibson, K.M., Cortez, M.A., Wu, Y., Snead, O.C., Knerr, I., Forester, K., Pettiford, J.M., Jakobs, C., Theodore, W.H. (2009), Succinic semialdehyde dehydrogenase deficiency: Lessons from Mice and Men., In Pearl, P.L., Gibson, K.M., Cortez, M.A., Wu, Y., Snead, O.C., Knerr, I., Forester, K., Pettiford, J.M., Jakobs, C., Theodore, W.H., Journal of Inherited Metabolism Disorders.

Journal Article, Pearl, P.L. (2009), New Treatment Paradigms in Neonatal Seizures, Journal of Inherited Metabolism Disorders , 32, 204-213.

Journal Article, Pearl, P.L., Vezina, L.G., Saneto, R.P., McCarter, R., Molloy-Wells, E., Heffron, A., Trzcinski, S., McClintock, W.M., Conry, J.A., Elling, N.J., Goodkin, H.P., Sotero de Menezes, M., Ferri, R., Gille (2009), Cerebral MRI Abnormalities Associated with Vigabatrin Therapy, Epilepsia, 50, 184-194.

Journal Article, Knerr, I., Gibson, K. M., Jakobs, C., Pearl, P. L. (2008), Neuropsychiatric Morbidity in Adolescent and Adult Succinic Semialdehyde Dehydrogenase Deficiency Patients, CNS Spectrum, 598-605.

Journal Article, Pearl, P. L., Conry, J. A., Yaun, A., Taylor, J. L., Heffron, A. M., Sigman, M. M., Tsuchida, T. T., Elling, N. J., Bruce, D. A., Gaillard, W. D. (2008), Misidentification of Vagus Nerve Stimulator for IV access and other major adverse events, Pediatric Neurology, 38, 248-251.

Journal Article, Pearl, P.L., Conry, J.A., et al. (2008), Misidentification of Vagus Nerve Stimulator for IV access and other major adverse, Pediatric Neurology, 38, 248-251.

Book Chapter, Pearl, P. L., Jakobs, C., Gibson, K. M., Scriver CR et al, editors (2007), The Neurological Examination – Pediatrics, In Pearl, P. L., Jakobs, C., Gibson, K. M., Scriver CR et al, editors, Online Molecular and Metabolic Bases of Inherited Disease.

Journal Article, Pearl, P. L., Taylor, J., Trzcinski, S., Sokohl, A. (2007), Pediatric Neurotransmitter Disorders, Journal of Child Neurology, 22, 606-616.

Journal Article, Knerr, I., Pearl, P. L., Bottiglieri, T., Snead, O.C., Jakobs, C., Gibson, K. M. (2007), Therapeutic Concepts in Succinate Semialdehyde Dehydrogenase (SSADH; ALDH5a1) Deficiency (Gamma-Hydroxybutyric Aciduria) - Hypotheses evolved from 25 years of patient evaluation, studies in Aldh5a1-/-, Journal of Inherited Metabolism Disorders, 30, 279-297.


For a more comprehensive list of publications for Phillip Pearl, MD view the National Library of Medicine’s PubMed online database

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