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Phillip L. Pearl, MD
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Center of Excellence, Departments, and Programs
The Center for Neuroscience and Behavioral Medicine Division Chief, Neurology
Children’s Research Institute (CRI) Center for Neuroscience Research View CRI Profile for Phillip L. Pearl Specialties: Epilepsy, Neurometabolic Disorders , Neurogenetic Disorders , Seizures
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| Board Certifications |
American Board of Psychiatry/Neurology-Neurophysio American Board of Pediatrics American Board of Psychiatry and Neurology
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National Provider Identifier
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1902983257 |
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| Practice Locations |
Children's National Medical Center - Main Hospital 111 Michigan Avenue, NW Washington, DC Phone: 202-476-5000
 Children's Outpatient Center of Northern Virginia 8501 Arlington Boulevard Suite 200 Fairfax, VA 22031 Phone: 571-226-8380
Fax: 571-226-8312

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| Biography |
| Phillip L. Pearl, MD, is chief of the Division of Neurology, interim director of Developmental Pediatrics, and director of Medical Student Education (Neurology) at George Washington University School of Medicine. The division of General Neurology is one of the largest pediatric neurology practices in the area, serving the greater Washington, DC/Maryland/Northern Virginia region through outpatient centers located at Children's main campus, as well as through its Regional Outpatient Centers and a number of satellite offices. Dr. Pearl's research interests are focused in epilepsy and neurotransmitter disorders, specifically SSADH deficiency. He serves as an investigator in protocols at Children's National Medical Center and the National Institutes of Health, and in that capacity makes the best practices in pediatric neurological care available to the patients and families for whom he cares. In addition to his impressive work in clinical care and research, Dr. Pearl is a jazz musician and frequently plays at area venues, including Blues Alley. |
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| Education |
| Type | School | Location | Degree | Field of Study | Years | | Undergraduate Education | Johns Hopkins University | Baltimore, MD | Bachelor of Arts | | 1980 | | Medical School | University of Maryland School of Medicine | Baltimore, MD | Doctor of Medicine | | 1984 |
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| Training |
| Type | Institution | Location | Position | Specialty | Years | | Residency Program | Baylor College of Medicine | Houston, TX | Resident | Pediatrics | 1984 - 1986 | | Fellowship Program | Baylor College of Medicine | Houston, TX | Fellow | Neurology | 1986 - 1989 | | Fellowship Program | Harvard Medical School | Boston, MA | Fellow | Neurophysiology | 1989 - 1990 |
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| National and International Recognition |
| Award | Institution | Event | Year | | Best Doctors | Northern Virginia Magazine | | 2008 | | Distinguished Clinical Teacher | George Washington University School of Medicine | | 2005 | | America’s Top Physicians | Consumers’ Research Council of America | | 2004 | | Humanism in Medicine | | | 2004 | | | | | | Faculty Award - Humanism in Medicine | Association of American Medical Colleges | | |
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| Affiliations and Memberships |
| Title | Institution | Committee / Section | Years | | Member | American Neurological Association | | 2006 - 2009 | | Member | American Pediatric Society | | 2006 - 2009 | | Chairman | Child Neurology Society | Awards Committee | 2004 - 2009 | | Secretary/Treasurer | Professors of Child Neurology | | 2006 - 2009 | | Member | American Epilepsy Society | Practice Committee | 2000 - 2003 |
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| Research |
| Title | Study Name | Institution | Years | | Principal Investigator | Clinical Studies on SSADH Deficiency | Pediatric Neurotransmitter Disease Association | 2007 - 2009 | | | Principal Investigator | Cerebral MRI Abnormalities Associated with Vigabatrin Therapy | Children's National Medical Center/ Institutional Review Board | 2006 | | | Investigator | Cortical Excitability in SSADH Deficiency Patients | Institutional Review Board/ National Institute of Neurological Disorders and Stroke/ National Instit | 2005 | | | Principal Investigator | Collection of Specimens for the Development of Diagnostic Assays of Neurotransmitter Disorders | Institutional Review Board | 2004 | | | Principal Investigator | Questionnaire Study of SSADH Deficiency | Institutional Review Board | 2004 | | | Read more about the research interests of Phillip L. Pearl |
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| Publications |
Journal Article, Hsieh D. T., Pearl P. L (2009), Teaching Video NeuroImages: preserved awareness in a frontal seizure with bilateral motor involvement: a psychogenic mimic., Neurology, 72, 56-56.
Book Chapter, Pearl, P.L., Gibson, K.M., Cortez, M.A., Wu, Y., Snead, O.C., Knerr, I., Forester, K., Pettiford, J.M., Jakobs, C., Theodore, W.H. (2009), Succinic semialdehyde dehydrogenase deficiency: Lessons from Mice and Men., In Pearl, P.L., Gibson, K.M., Cortez, M.A., Wu, Y., Snead, O.C., Knerr, I., Forester, K., Pettiford, J.M., Jakobs, C., Theodore, W.H., Journal of Inherited Metabolism Disorders.
Journal Article, Pearl, P.L. (2009), New Treatment Paradigms in Neonatal Seizures, Journal of Inherited Metabolism Disorders , 32, 204-213.
Journal Article, Pearl, P.L., Vezina, L.G., Saneto, R.P., McCarter, R., Molloy-Wells, E., Heffron, A., Trzcinski, S., McClintock, W.M., Conry, J.A., Elling, N.J., Goodkin, H.P., Sotero de Menezes, M., Ferri, R., Gille (2009), Cerebral MRI Abnormalities Associated with Vigabatrin Therapy, Epilepsia, 50, 184-194.
Journal Article, Knerr, I., Gibson, K. M., Jakobs, C., Pearl, P. L. (2008), Neuropsychiatric Morbidity in Adolescent and Adult Succinic Semialdehyde Dehydrogenase Deficiency Patients, CNS Spectrum, 598-605.
Journal Article, Pearl, P. L., Conry, J. A., Yaun, A., Taylor, J. L., Heffron, A. M., Sigman, M. M., Tsuchida, T. T., Elling, N. J., Bruce, D. A., Gaillard, W. D. (2008), Misidentification of Vagus Nerve Stimulator for IV access and other major adverse events, Pediatric Neurology, 38, 248-251.
Journal Article, Pearl, P.L., Conry, J.A., et al. (2008), Misidentification of Vagus Nerve Stimulator for IV access and other major adverse, Pediatric Neurology, 38, 248-251.
Book Chapter, Pearl, P. L., Jakobs, C., Gibson, K. M., Scriver CR et al, editors (2007), The Neurological Examination – Pediatrics, In Pearl, P. L., Jakobs, C., Gibson, K. M., Scriver CR et al, editors, Online Molecular and Metabolic Bases of Inherited Disease.
Journal Article, Pearl, P. L., Taylor, J., Trzcinski, S., Sokohl, A. (2007), Pediatric Neurotransmitter Disorders, Journal of Child Neurology, 22, 606-616.
Journal Article, Knerr, I., Pearl, P. L., Bottiglieri, T., Snead, O.C., Jakobs, C., Gibson, K. M. (2007), Therapeutic Concepts in Succinate Semialdehyde Dehydrogenase (SSADH; ALDH5a1) Deficiency (Gamma-Hydroxybutyric Aciduria) - Hypotheses evolved from 25 years of patient evaluation, studies in Aldh5a1-/-, Journal of Inherited Metabolism Disorders, 30, 279-297.
For a more comprehensive list of publications for Phillip Pearl, MD view the National Library of Medicine’s PubMed online database |
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