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Meet the team
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Catherine Limperopoulos, PhD
Director/Principal Investigator
Dr. Limperopoulos is the Director and Principal Investigator of the Advanced Pediatric Brain Imaging Laboratory and Associate Professor of Pediatrics at George Washington University School of Medicine and Health Sciences. Her research activities focus on studying the causes and consequences of early life brain injury in high-risk fetal, preterm, and full-term infant populations. Central to her research is the application of advanced magnetic resonance imaging (MRI) techniques to identify important biomarkers and understand the timing and evolution of brain injury as well as the brain's adaptive response following injury. The long-term goals of the research program are to guide medical and rehabilitation interventions aimed at preventing brain injury and minimizing long-term developmental disability. |
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Marine Bouyssi-Kobar, Ms BME
MRI Clinical Research Assistant
Marine is a biomedical engineer with experience in pediatric clinical research. Her interdisciplinary work includes MRI data management and image processing in order to develop novel, non-invasive brain imaging techniques to study the mechanisms and consequences of brain injury in high-risk fetal and neonatal populations. She also works closely with scientists, MRI technologists, nursing staff, and physicians to ensure patient comfort and safety during MRI research studies as well as optimal scanning performances. Finally, she is involved in teaching advanced MRI post-processing techniques to trainees and medical fellows. |
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Marie Brossard-Racine, PhD
Post-doctoral Fellow
Dr. Brossard-Racine is a child health clinician scientist. She has a clinical-research background in children with developmental disabilities. Under the supervision of the principal investigator using advanced multimodal MRI post-processing techniques, including volumetric, diffusion tensor, and functional imaging methods, she is studying brain injury in high-risk fetuses, premature infants, and newborns with critical congenital heart disease. Her research interests focus on understanding the underlying mechanisms of early life brain injury that lead to lifelong childhood disabilities.
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Cedric Clouchoux, PhD
Research Faculty
Dr. Clouchoux is Research Faculty at the Advanced Pediatric Brain Imaging Research Laboratory. His background is in biomedical engineering and image processing. His research interests are the characterization and the quantification of the in vivo fetal brain development, and more specifically focused on the cerebral cortex. The two main aspects of this work are developing advanced image processing tools to evaluate brain growth, and quantifying the evolution of anatomical structures and cortical folding during the antenatal life for both normal and high-risk fetuses.
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Safiya Davy, RN, BSN
Research Nurse Coordinator
Safiya Davy is the Research Nurse Coordinator for the cerebellar brain development study and works actively on the congenital heart disease study. Her background is in computer information systems and neonatal intensive care (NICU) nursing. As part of the Advanced Pediatric Brain Imaging Program, her role is to recruit and consent potential research patients for the respective studies, assist in the development of web-based data collection programs, and work effectively with all of the members of the interdisciplinary team to ensure that the NICU research patients and their families are closely monitored and informed of pertinent research related activities.
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Iordanis Evangelou, DPhil,
Research Faculty
Dr. Evangelou is Research Faculty, and Assistant Professor of Pediatrics at George Washington University School of Medicine and Health Sciences. His research interests are novel MRI acquisition and post-processing techniques to quantitatively measure tissue changes occurring during normal development and with disease, targeted to the placental, fetal and neonatal brain and spinal cord tissues in vivo. Moreover, developing, extending, and implementing algorithms for image segmentation, registration, motion correction, distortion correction, diffusion tensor processing, magnetic resonance spectroscopy, and quantitative relaxation times mapping. Specifically, developing automated post-processing pipelines that execute several of the pre-processing and post-processing tasks required to perform both cross-sectional and large-scale longitudinal measurements of MRI data with minimal user intervention.
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Dena Freeman, MPH
Clinical Research Coordinator
Dena is the Clinical Research Coordinator for the Advanced Pediatric Brain Imaging Research Laboratory. Her background is in biochemistry and molecular biology and public health genetics. She is primarily responsible for recruiting patients and coordinating all study-related activities for Brain Development in the Fetus with Congenital Heart Disease. As part of the Advanced Pediatric Brain Imaging Research Program, Dena designs and implements best practices for MRI study visits. She also serves as a mentor for other research coordinators utilizing MRI studies in their protocols. |
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Géraldine Pluviose, BS
Operations Coordinator
Géraldine is the Operations Coordinator for the Advanced Pediatric Brain Imaging Research Laboratory. Her background is in Business. Geraldine works directly with the Director on many ongoing projects. She is primarily responsible for the ongoing daily operations of clinical research related business, and research study facilitation. Géraldine participates in planning, directing and implementing projects, assists in the development, monitoring and implementation of a cost-effective budget. Géraldine also coordinates and monitors payroll, schedules and non-clinical systems.
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James R. Reese (Robbie)
Sr. Systems Engineer
Robbie is the Sr. Systems Engineer for the Advanced Pediatric Brain Imaging Research Laboratory. Robbie is managing the IT infrastructure needed by the research faculty. He has extensive experience developing and implementing highly available computer architectures, complex computer networks, and virtualization platforms. He has worked as a Systems Administrator/Engineer for over 12 years. The main aspects of his work are providing smooth operation of the systems that support the team and researching ways that technology will help them in the future. |
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Ahmed Serag, PhD
Research Post-doctoral Fellow
Ahmed Serag is a Research Fellow at the Advanced Pediatric Brain Imaging Research Laboratory. Ahmed has extensive experience in image processing techniques in 3D and 4D medical images with an emphasis on registration, segmentation, and machine learning. He previously developed medical image analysis tools for Philips, Siemens, Imperial College London, Leiden University Medical Center, and University Medical Center Hamburg-Eppendorf. His research is focused on understanding normal brain growth patterns and mechanisms of injury to the immature brain in high-risk populations including the fetus and infant with congenital heart disease, and infants born prematurely. He is particularly interested in developing automatic algorithms and software tools for Computer Aided Diagnosis (CAD) of neurological damage in the developing brain to improve care for high-risk infants
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